CAT #: F70101C-AC-2

LIPID COMPOSITION: Phosphatidylglycerol, phosphatidylcholine and cholesterol

ACTIVE: Clodronate: (Dichloromethylene) bisphosphonic acid disodium salt tetrahydrate (CAS:88416-50-6, 22560-50-5)

CLODRONATE CONCENTRATION: 7 mg/mL

CLODRONATE ENCAPSULATION: >90%

BULK SOLUTION: PBS (10% sucrose, 20mM Na PO4), pH 7.0-7.4

FORM/COLOR: Milky and free flow liposomal dispersion, Some settlement of the liposome particles may occur which should disperse with proper mixing

STORAGE AND HANDLING: Store refrigerated (2-8 deg C). Avoid freezing. Warm to room temperature and mix well before use 

RECOMMENDED DOSE: 

 For macrophage depletion up to one week: 200 uL day 1 (for 20-25g mouse) For more consistent results inject 2 days in advance For longer macrophage depletion: 200uL first dose, 100uL every 4 days 

STABILITY AND GUARANTEE: 

Product is sterile filtered and filled in autoclaved glass vials. Formulation stability and sterility are guaranteed for 3 months stored at 2 – 8 oC